STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3R577_GORGOInsulin like growth factor binding protein 1. (259 aa)    
Predicted Functional Partners:
IGF1
IlGF domain-containing protein.
   
 0.998
IGF2
Insulin like growth factor 2.
   
 0.988
IGFBP4
Insulin like growth factor binding protein 4.
   
 
0.929
AHSG
Alpha 2-HS glycoprotein.
   
  
 0.864
G3QEZ4_GORGO
Left-right determination factor.
      
 0.752
ESF1
ESF1 nucleolar pre-rRNA processing protein homolog.
      
 0.718
IGF1R
Tyrosine-protein kinase receptor.
   
 
 0.679
AFP
Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin.
   
  
 0.676
INS
Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      
 0.672
CORIN
Corin, serine peptidase.
    
 0.646
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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