STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FXYD4FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (89 aa)    
Predicted Functional Partners:
GJD4
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.773
FXYD7
FXYD domain-containing ion transport regulator; Belongs to the FXYD family.
     
 0.593
G3S4V1_GORGO
FXYD domain-containing ion transport regulator; Belongs to the FXYD family.
      
 0.572
FXYD5
FXYD domain-containing ion transport regulator; Belongs to the FXYD family.
     
 0.539
G3RUQ5_GORGO
FXYD domain-containing ion transport regulator; Belongs to the FXYD family.
  
   
 0.479
ATP1B2
Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.
    
 0.461
SPINK14
Serine peptidase inhibitor, Kazal type 14 (putative).
   
  
 0.453
ATP1B1
Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.
    
 0.448
SPINK9
Kazal-like domain-containing protein.
   
  
 0.438
SPINK7
Serine peptidase inhibitor, Kazal type 7 (putative).
   
  
 0.407
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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