STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)    
Predicted Functional Partners:
TNFRSF11A
TNF receptor superfamily member 11a.
    
 0.999
TNFRSF11B
Death domain-containing protein.
   
 0.997
ENSGGOP00000032308
TNFR-Cys domain-containing protein.
   
 0.973
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 
 0.859
CSF1R
Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
  
 0.814
TNFSF13B
TNF superfamily member 13b; Belongs to the tumor necrosis factor family.
   
 0.797
ACP5
Tartrate-resistant acid phosphatase type 5.
      
 0.776
CTSK
Cathepsin K; Belongs to the peptidase C1 family.
   
  
 0.768
LTBR
Lymphotoxin beta receptor.
   
 0.756
CD40
CD40 molecule.
   
 0.727
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.