STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHIT1Chitinase 1; Belongs to the glycosyl hydrolase 18 family. (465 aa)    
Predicted Functional Partners:
HEXA
Beta-hexosaminidase.
    
 0.930
G3QZM1_GORGO
Chitinase acidic; Belongs to the glycosyl hydrolase 18 family.
  
  
 
0.902
RENBP
Renin binding protein.
     
  0.900
NAGK
N-acetylglucosamine kinase.
     
  0.900
PAGE1
PAGE family member 1.
      
 0.719
DCD
Dermcidin.
      
 0.680
UGCG
UDP-glucose ceramide glucosyltransferase.
      
 0.674
ENSGGOP00000035164
Glucosylceramidase.
      
 0.673
COX3
Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]
    
 0.663
G3QFP8_GORGO
Cytochrome c oxidase subunit 5B.
   
 0.659
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.