STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAC3Rac family small GTPase 3. (180 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.968
PAK1
Non-specific serine/threonine protein kinase.
   
 0.928
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.925
G3RCS6_GORGO
Trio Rho guanine nucleotide exchange factor.
   
 0.916
DOCK10
Dedicator of cytokinesis 10; Belongs to the DOCK family.
   
 0.909
G3SKN5_GORGO
Dedicator of cytokinesis 2; Belongs to the DOCK family.
   
 0.904
DOCK5
Dedicator of cytokinesis 5; Belongs to the DOCK family.
   
 0.903
PAK4
Non-specific serine/threonine protein kinase.
   
 0.901
ELMO1
Engulfment and cell motility 1.
    
 0.899
PLXNB1
Plexin B1.
   
 0.897
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.