STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHG6Pleckstrin homology and RhoGEF domain containing G6. (790 aa)    
Predicted Functional Partners:
PLEKHG4B
Pleckstrin homology and RhoGEF domain containing G4B.
     
 0.715
G3QT76_GORGO
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
    
 0.704
TRADD
Death domain-containing protein.
    
 0.694
RHOA
Uncharacterized protein.
    
 0.694
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.689
ARHGEF11
Rho guanine nucleotide exchange factor 11.
    
0.668
G3QT71_GORGO
Lymphotoxin alpha; Belongs to the tumor necrosis factor family.
    
 0.662
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
    
 0.655
TNFSF15
TNF superfamily member 15.
    
 0.642
RHOG
Ras homolog family member G.
   
 0.640
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.