STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITIH2Inter-alpha-trypsin inhibitor heavy chain 2. (946 aa)    
Predicted Functional Partners:
AHSG
Alpha 2-HS glycoprotein.
   
 0.890
G3R1H9_GORGO
Apolipoprotein H.
   
 0.869
AMBP
Alpha-1-microglobulin/bikunin precursor.
   
  
 0.789
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.761
VTN
Vitronectin.
   
 0.759
ITIH1
Inter-alpha-trypsin inhibitor heavy chain 1.
  
  
0.691
ALB
Albumin.
   
 
 0.671
APOB
Apolipoprotein B.
   
 
 0.621
FGA
Fibrinogen alpha chain.
   
 
 0.612
ITIH3
Inter-alpha-trypsin inhibitor heavy chain 3.
  
  
0.590
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.