STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STIP1Stress induced phosphoprotein 1. (590 aa)    
Predicted Functional Partners:
G3S4Z2_GORGO
Uncharacterized protein.
   
 0.979
HSP90AB1
Heat shock protein 90 alpha family class B member 1.
   
 0.974
HSPA8
Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family.
  
 0.970
PRNP
Major prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase deg [...]
    
 0.966
ENSGGOP00000034582
Uncharacterized protein.
  
 0.956
HSPA4
Heat shock protein family A (Hsp70) member 4.
  
 0.954
ENSGGOP00000047188
Uncharacterized protein; Belongs to the heat shock protein 70 family.
  
 0.939
G3S9G1_GORGO
Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family.
  
 0.934
NR3C1
Nuclear receptor subfamily 3 group C member 1.
   
 0.934
AHSA1
Activator of HSP90 ATPase activity 1.
   
 
 0.890
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.