| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARID3A | LBX1 | ENSGGOP00000000593 | ENSGGOP00000012209 | AT-rich interaction domain 3A. | Ladybird homeobox 1. | 0.459 |
| ARID3A | MAFG | ENSGGOP00000000593 | ENSGGOP00000028028 | AT-rich interaction domain 3A. | MAF bZIP transcription factor G. | 0.716 |
| BTRC | DPCD | ENSGGOP00000020770 | ENSGGOP00000004932 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | Deleted in primary ciliary dyskinesia homolog (mouse). | 0.414 |
| BTRC | ENSGGOP00000036799 | ENSGGOP00000020770 | ENSGGOP00000036799 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] | 0.518 |
| BTRC | FBXW4 | ENSGGOP00000020770 | ENSGGOP00000020785 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | F-box and WD repeat domain containing 4. | 0.530 |
| BTRC | LBX1 | ENSGGOP00000020770 | ENSGGOP00000012209 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | Ladybird homeobox 1. | 0.412 |
| BTRC | POLL | ENSGGOP00000020770 | ENSGGOP00000004928 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. | 0.409 |
| DPCD | BTRC | ENSGGOP00000004932 | ENSGGOP00000020770 | Deleted in primary ciliary dyskinesia homolog (mouse). | Beta-transducin repeat containing E3 ubiquitin protein ligase. | 0.414 |
| DPCD | FBXW4 | ENSGGOP00000004932 | ENSGGOP00000020785 | Deleted in primary ciliary dyskinesia homolog (mouse). | F-box and WD repeat domain containing 4. | 0.699 |
| DPCD | LBX1 | ENSGGOP00000004932 | ENSGGOP00000012209 | Deleted in primary ciliary dyskinesia homolog (mouse). | Ladybird homeobox 1. | 0.638 |
| DPCD | POLL | ENSGGOP00000004932 | ENSGGOP00000004928 | Deleted in primary ciliary dyskinesia homolog (mouse). | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. | 0.622 |
| ENSGGOP00000036799 | BTRC | ENSGGOP00000036799 | ENSGGOP00000020770 | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] | Beta-transducin repeat containing E3 ubiquitin protein ligase. | 0.518 |
| ENSGGOP00000036799 | FBXW4 | ENSGGOP00000036799 | ENSGGOP00000020785 | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] | F-box and WD repeat domain containing 4. | 0.409 |
| ENSGGOP00000036799 | LBX1 | ENSGGOP00000036799 | ENSGGOP00000012209 | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] | Ladybird homeobox 1. | 0.405 |
| ENSGGOP00000036799 | POLL | ENSGGOP00000036799 | ENSGGOP00000004928 | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. | 0.402 |
| FBXW4 | BTRC | ENSGGOP00000020785 | ENSGGOP00000020770 | F-box and WD repeat domain containing 4. | Beta-transducin repeat containing E3 ubiquitin protein ligase. | 0.530 |
| FBXW4 | DPCD | ENSGGOP00000020785 | ENSGGOP00000004932 | F-box and WD repeat domain containing 4. | Deleted in primary ciliary dyskinesia homolog (mouse). | 0.699 |
| FBXW4 | ENSGGOP00000036799 | ENSGGOP00000020785 | ENSGGOP00000036799 | F-box and WD repeat domain containing 4. | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] | 0.409 |
| FBXW4 | LBX1 | ENSGGOP00000020785 | ENSGGOP00000012209 | F-box and WD repeat domain containing 4. | Ladybird homeobox 1. | 0.696 |
| FBXW4 | POLL | ENSGGOP00000020785 | ENSGGOP00000004928 | F-box and WD repeat domain containing 4. | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. | 0.670 |
