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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHOAUncharacterized protein. (179 aa)    
Predicted Functional Partners:
AKAP13
A-kinase anchoring protein 13.
   
 0.999
ROCK1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
   
 0.999
ARHGEF12
Rho guanine nucleotide exchange factor 12.
   
 0.999
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2.
   
 0.998
ARHGEF11
Rho guanine nucleotide exchange factor 11.
   
 0.998
ARHGEF1
Rho guanine nucleotide exchange factor 1.
   
 0.995
ARHGAP35
Rho GTPase activating protein 35.
    
 0.995
G3QPY2_GORGO
Uncharacterized protein.
   
 0.994
ENSGGOP00000040427
Rho GDP dissociation inhibitor alpha.
   
 0.994
ROCK2
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
 0.993
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.