IGF1R protein (Gorilla gorilla) - STRING interaction network

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Score

IGF1R

Tyrosine-protein kinase receptor. (1367 aa)

Predicted Functional Partners:

IGF1

0.999

IRS1

0.999

IGF2

0.999

GRB10

0.997

INS

0.997

INSR

0.993

SHC1

0.992

PIK3R1

0.986

PTPN1

0.983

EGF

0.982

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGF	GRB10	ENSGGOP00000005698	ENSGGOP00000006350	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Growth factor receptor bound protein 10.	0.537
EGF	IGF1	ENSGGOP00000005698	ENSGGOP00000004843	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	IlGF domain-containing protein.	0.974
EGF	IGF1R	ENSGGOP00000005698	ENSGGOP00000012531	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.982
EGF	IGF2	ENSGGOP00000005698	ENSGGOP00000047744	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Insulin like growth factor 2.	0.459
EGF	INS	ENSGGOP00000005698	ENSGGOP00000034798	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.979
EGF	INSR	ENSGGOP00000005698	ENSGGOP00000018071	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.963
EGF	PIK3R1	ENSGGOP00000005698	ENSGGOP00000050489	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Phosphoinositide-3-kinase regulatory subunit 1.	0.766
EGF	PTPN1	ENSGGOP00000005698	ENSGGOP00000006885	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein phosphatase non-receptor type.	0.539
EGF	SHC1	ENSGGOP00000005698	ENSGGOP00000013082	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	SHC adaptor protein 1.	0.696
GRB10	EGF	ENSGGOP00000006350	ENSGGOP00000005698	Growth factor receptor bound protein 10.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.537
GRB10	IGF1	ENSGGOP00000006350	ENSGGOP00000004843	Growth factor receptor bound protein 10.	IlGF domain-containing protein.	0.787
GRB10	IGF1R	ENSGGOP00000006350	ENSGGOP00000012531	Growth factor receptor bound protein 10.	Tyrosine-protein kinase receptor.	0.997
GRB10	IGF2	ENSGGOP00000006350	ENSGGOP00000047744	Growth factor receptor bound protein 10.	Insulin like growth factor 2.	0.722
GRB10	INS	ENSGGOP00000006350	ENSGGOP00000034798	Growth factor receptor bound protein 10.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.738
GRB10	INSR	ENSGGOP00000006350	ENSGGOP00000018071	Growth factor receptor bound protein 10.	Tyrosine-protein kinase receptor.	0.995
GRB10	IRS1	ENSGGOP00000006350	ENSGGOP00000031038	Growth factor receptor bound protein 10.	Insulin receptor substrate 1.	0.716
GRB10	PIK3R1	ENSGGOP00000006350	ENSGGOP00000050489	Growth factor receptor bound protein 10.	Phosphoinositide-3-kinase regulatory subunit 1.	0.921
GRB10	SHC1	ENSGGOP00000006350	ENSGGOP00000013082	Growth factor receptor bound protein 10.	SHC adaptor protein 1.	0.434
IGF1	EGF	ENSGGOP00000004843	ENSGGOP00000005698	IlGF domain-containing protein.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.974
IGF1	GRB10	ENSGGOP00000004843	ENSGGOP00000006350	IlGF domain-containing protein.	Growth factor receptor bound protein 10.	0.787