SCN5A protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSGGOP00000032040	PRKACB	ENSGGOP00000032040	ENSGGOP00000025699	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.999
ENSGGOP00000032040	SCN1B	ENSGGOP00000032040	ENSGGOP00000045670	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Sodium voltage-gated channel beta subunit 1.	0.900
ENSGGOP00000032040	SCN4B	ENSGGOP00000032040	ENSGGOP00000002061	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Sodium voltage-gated channel beta subunit 4.	0.900
ENSGGOP00000032040	SCN5A	ENSGGOP00000032040	ENSGGOP00000012641	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.935
ENSGGOP00000032040	SCN7A	ENSGGOP00000032040	ENSGGOP00000002078	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.927
G3S8D3_GORGO	SCN1B	ENSGGOP00000024346	ENSGGOP00000045670	Calcium/calmodulin dependent protein kinase II delta.	Sodium voltage-gated channel beta subunit 1.	0.900
G3S8D3_GORGO	SCN4B	ENSGGOP00000024346	ENSGGOP00000002061	Calcium/calmodulin dependent protein kinase II delta.	Sodium voltage-gated channel beta subunit 4.	0.901
G3S8D3_GORGO	SCN5A	ENSGGOP00000024346	ENSGGOP00000012641	Calcium/calmodulin dependent protein kinase II delta.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.922
G3S8D3_GORGO	SCN7A	ENSGGOP00000024346	ENSGGOP00000002078	Calcium/calmodulin dependent protein kinase II delta.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.915
PRKACB	ENSGGOP00000032040	ENSGGOP00000025699	ENSGGOP00000032040	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.999
PRKACB	SCN1B	ENSGGOP00000025699	ENSGGOP00000045670	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	Sodium voltage-gated channel beta subunit 1.	0.900
PRKACB	SCN4B	ENSGGOP00000025699	ENSGGOP00000002061	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	Sodium voltage-gated channel beta subunit 4.	0.900
PRKACB	SCN5A	ENSGGOP00000025699	ENSGGOP00000012641	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.935
PRKACB	SCN7A	ENSGGOP00000025699	ENSGGOP00000002078	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.927
SCN1B	ENSGGOP00000032040	ENSGGOP00000045670	ENSGGOP00000032040	Sodium voltage-gated channel beta subunit 1.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.900
SCN1B	G3S8D3_GORGO	ENSGGOP00000045670	ENSGGOP00000024346	Sodium voltage-gated channel beta subunit 1.	Calcium/calmodulin dependent protein kinase II delta.	0.900
SCN1B	PRKACB	ENSGGOP00000045670	ENSGGOP00000025699	Sodium voltage-gated channel beta subunit 1.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.900
SCN1B	SCN3A	ENSGGOP00000045670	ENSGGOP00000016440	Sodium voltage-gated channel beta subunit 1.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.875
SCN1B	SCN4A	ENSGGOP00000045670	ENSGGOP00000012234	Sodium voltage-gated channel beta subunit 1.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.932
SCN1B	SCN4B	ENSGGOP00000045670	ENSGGOP00000002061	Sodium voltage-gated channel beta subunit 1.	Sodium voltage-gated channel beta subunit 4.	0.977