STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (670 aa)    
Predicted Functional Partners:
G3S7H0_GORGO
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
  
 
0.953
ITSN2
Intersectin 2.
   
 0.909
DCC
DCC netrin 1 receptor.
   
 0.903
IGDCC3
Immunoglobulin superfamily DCC subclass member 3.
   
  0.896
IGDCC4
Immunoglobulin superfamily DCC subclass member 4.
   
  0.896
G3SG23_GORGO
Neogenin 1.
   
  0.896
FNDC1
Fibronectin type III domain containing 1.
    
  0.894
RAB5A
RAB5A, member RAS oncogene family.
   
 
 0.783
G3SAY4_GORGO
Uncharacterized protein.
   
 
 0.774
RAB17
RAB17, member RAS oncogene family.
   
 
 0.761
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.