STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)    
Predicted Functional Partners:
CCNB1
Cyclin B1; Belongs to the cyclin family.
   
 0.999
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 0.999
CCNB2
Cyclin B2; Belongs to the cyclin family.
   
 0.999
CCNA1
Cyclin A1; Belongs to the cyclin family.
   
 0.999
CDC25B
Cell division cycle 25B.
   
 0.995
WEE1
Wee1-like protein kinase.
   
 0.994
CKS2
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.994
GADD45A
Growth arrest and DNA damage inducible alpha.
    
 0.992
G3SH76_GORGO
Anaphase promoting complex subunit 4.
    
 0.991
TOP2A
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
 
 0.990
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.