STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COP1COP1 E3 ubiquitin ligase. (734 aa)    
Predicted Functional Partners:
DET1
Uncharacterized protein.
    
 0.992
DDB1
Damage specific DNA binding protein 1.
    
 0.976
DDB2
Damage specific DNA binding protein 2.
    
 0.968
ERCC8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit.
    
  0.952
CUL4A
Cullin 4A; Belongs to the cullin family.
   
 0.948
G3QRE4_GORGO
Tribbles pseudokinase 1.
    
 
 0.881
ENSGGOP00000051310
ETS variant 1.
    
 
 0.878
ETV5
ETS variant 5.
    
 
 0.871
TRIB3
Tribbles pseudokinase 3.
    
 
 0.871
G3QLU7_GORGO
RING-type domain-containing protein.
    
 0.861
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.