node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASNA1 | BAG6 | ENSGGOP00000005430 | ENSGGOP00000040281 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | BCL2 associated athanogene 6. | 0.913 |
ASNA1 | G3RA78_GORGO | ENSGGOP00000005430 | ENSGGOP00000012337 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Guided entry of tail-anchored proteins factor 4. | 0.982 |
ASNA1 | SGTA | ENSGGOP00000005430 | ENSGGOP00000007741 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Small glutamine rich tetratricopeptide repeat containing alpha. | 0.870 |
ASNA1 | UBL4A | ENSGGOP00000005430 | ENSGGOP00000013176 | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | Ubiquitin-like domain-containing protein. | 0.970 |
BAG6 | ASNA1 | ENSGGOP00000040281 | ENSGGOP00000005430 | BCL2 associated athanogene 6. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.913 |
BAG6 | FAF2 | ENSGGOP00000040281 | ENSGGOP00000016892 | BCL2 associated athanogene 6. | Fas associated factor family member 2. | 0.986 |
BAG6 | G3RA78_GORGO | ENSGGOP00000040281 | ENSGGOP00000012337 | BCL2 associated athanogene 6. | Guided entry of tail-anchored proteins factor 4. | 0.999 |
BAG6 | SGTA | ENSGGOP00000040281 | ENSGGOP00000007741 | BCL2 associated athanogene 6. | Small glutamine rich tetratricopeptide repeat containing alpha. | 0.982 |
BAG6 | UBL4A | ENSGGOP00000040281 | ENSGGOP00000013176 | BCL2 associated athanogene 6. | Ubiquitin-like domain-containing protein. | 0.999 |
ENSGGOP00000047423 | TRAF7 | ENSGGOP00000047423 | ENSGGOP00000017604 | UBIQUITIN_CONJUGAT_2 domain-containing protein. | TNF receptor associated factor 7. | 0.699 |
ENSGGOP00000047423 | UBL4A | ENSGGOP00000047423 | ENSGGOP00000013176 | UBIQUITIN_CONJUGAT_2 domain-containing protein. | Ubiquitin-like domain-containing protein. | 0.892 |
FAF2 | BAG6 | ENSGGOP00000016892 | ENSGGOP00000040281 | Fas associated factor family member 2. | BCL2 associated athanogene 6. | 0.986 |
FAF2 | UBL4A | ENSGGOP00000016892 | ENSGGOP00000013176 | Fas associated factor family member 2. | Ubiquitin-like domain-containing protein. | 0.849 |
FAF2 | UBXN7 | ENSGGOP00000016892 | ENSGGOP00000014398 | Fas associated factor family member 2. | UBX domain-containing protein 7. | 0.995 |
G3RA78_GORGO | ASNA1 | ENSGGOP00000012337 | ENSGGOP00000005430 | Guided entry of tail-anchored proteins factor 4. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.982 |
G3RA78_GORGO | BAG6 | ENSGGOP00000012337 | ENSGGOP00000040281 | Guided entry of tail-anchored proteins factor 4. | BCL2 associated athanogene 6. | 0.999 |
G3RA78_GORGO | SGTA | ENSGGOP00000012337 | ENSGGOP00000007741 | Guided entry of tail-anchored proteins factor 4. | Small glutamine rich tetratricopeptide repeat containing alpha. | 0.980 |
G3RA78_GORGO | UBL4A | ENSGGOP00000012337 | ENSGGOP00000013176 | Guided entry of tail-anchored proteins factor 4. | Ubiquitin-like domain-containing protein. | 0.999 |
MYSM1 | TRAF7 | ENSGGOP00000005135 | ENSGGOP00000017604 | Myb like, SWIRM and MPN domains 1. | TNF receptor associated factor 7. | 0.536 |
MYSM1 | UBL4A | ENSGGOP00000005135 | ENSGGOP00000013176 | Myb like, SWIRM and MPN domains 1. | Ubiquitin-like domain-containing protein. | 0.944 |