STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRDM5Zinc finger protein. (630 aa)    
Predicted Functional Partners:
EDIL3
EGF like repeats and discoidin domains 3.
   
 
 0.803
PCOLCE2
Procollagen C-endopeptidase enhancer 2.
      
 0.752
GPC6
Glypican 6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
      
 0.700
HAPLN1
Hyaluronan and proteoglycan link protein 1.
    
 0.697
KNG1
Kininogen 1.
    
 
 0.681
G3R707_GORGO
Uroporphyrinogen III synthase.
    
 
 0.673
BTN1A1
Butyrophilin subfamily 1 member A1.
   
 0.576
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.557
COL11A1
Collagen type XI alpha 1 chain.
    
 0.536
GTF3C1
General transcription factor IIIC subunit 1.
    
 0.530
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.