INSRR protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRB2	IGF1	ENSGGOP00000005990	ENSGGOP00000004843	Growth factor receptor bound protein 2.	IlGF domain-containing protein.	0.593
GRB2	IGF1R	ENSGGOP00000005990	ENSGGOP00000012531	Growth factor receptor bound protein 2.	Tyrosine-protein kinase receptor.	0.973
GRB2	INS	ENSGGOP00000005990	ENSGGOP00000034798	Growth factor receptor bound protein 2.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.684
GRB2	INSR	ENSGGOP00000005990	ENSGGOP00000018071	Growth factor receptor bound protein 2.	Tyrosine-protein kinase receptor.	0.978
GRB2	INSRR	ENSGGOP00000005990	ENSGGOP00000013469	Growth factor receptor bound protein 2.	Tyrosine-protein kinase receptor.	0.952
GRB2	PIK3R1	ENSGGOP00000005990	ENSGGOP00000050489	Growth factor receptor bound protein 2.	Phosphoinositide-3-kinase regulatory subunit 1.	0.975
GRB2	PIK3R3	ENSGGOP00000005990	ENSGGOP00000019086	Growth factor receptor bound protein 2.	Uncharacterized protein.	0.842
GRB2	PTPN1	ENSGGOP00000005990	ENSGGOP00000006885	Growth factor receptor bound protein 2.	Tyrosine-protein phosphatase non-receptor type.	0.808
GRB2	SOS1	ENSGGOP00000005990	ENSGGOP00000022879	Growth factor receptor bound protein 2.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.999
GRB2	SOS2	ENSGGOP00000005990	ENSGGOP00000048825	Growth factor receptor bound protein 2.	SOS Ras/Rho guanine nucleotide exchange factor 2.	0.999
IGF1	GRB2	ENSGGOP00000004843	ENSGGOP00000005990	IlGF domain-containing protein.	Growth factor receptor bound protein 2.	0.593
IGF1	IGF1R	ENSGGOP00000004843	ENSGGOP00000012531	IlGF domain-containing protein.	Tyrosine-protein kinase receptor.	0.999
IGF1	INS	ENSGGOP00000004843	ENSGGOP00000034798	IlGF domain-containing protein.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.979
IGF1	INSR	ENSGGOP00000004843	ENSGGOP00000018071	IlGF domain-containing protein.	Tyrosine-protein kinase receptor.	0.995
IGF1	INSRR	ENSGGOP00000004843	ENSGGOP00000013469	IlGF domain-containing protein.	Tyrosine-protein kinase receptor.	0.926
IGF1	PIK3R1	ENSGGOP00000004843	ENSGGOP00000050489	IlGF domain-containing protein.	Phosphoinositide-3-kinase regulatory subunit 1.	0.459
IGF1	SOS1	ENSGGOP00000004843	ENSGGOP00000022879	IlGF domain-containing protein.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.507
IGF1R	GRB2	ENSGGOP00000012531	ENSGGOP00000005990	Tyrosine-protein kinase receptor.	Growth factor receptor bound protein 2.	0.973
IGF1R	IGF1	ENSGGOP00000012531	ENSGGOP00000004843	Tyrosine-protein kinase receptor.	IlGF domain-containing protein.	0.999
IGF1R	INS	ENSGGOP00000012531	ENSGGOP00000034798	Tyrosine-protein kinase receptor.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.995