Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
G3QYC6_GORGOCalpain 2; Belongs to the peptidase C2 family. (673 aa)    
Predicted Functional Partners:
CAPN1
Calpain 1; Belongs to the peptidase C2 family.
  
0.987
CAST
Calpastatin.
   
 0.963
TLN1
FERM domain-containing protein.
   
 0.941
CAPNS1
Calpain small subunit 1.
   
0.939
CDK5R1
Cyclin-dependent kinase 5 activator.
   
 0.939
G3SE26_GORGO
Talin 2.
   
 0.933
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
    
 0.918
G3R8R1_GORGO
Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family.
    
 0.912
BAX
BCL2 associated X, apoptosis regulator.
   
 0.906
IL1A
Interleukin-1; Belongs to the IL-1 family.
   
 
 0.903
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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