| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADK | ADSL | ENSGGOP00000005286 | ENSGGOP00000014747 | Adenosine kinase. | ADSL_C domain-containing protein. | 0.972 |
| ADK | AK3 | ENSGGOP00000005286 | ENSGGOP00000023329 | Adenosine kinase. | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 0.941 |
| ADK | AMPD1 | ENSGGOP00000005286 | ENSGGOP00000036589 | Adenosine kinase. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.957 |
| ADK | AMPD2 | ENSGGOP00000005286 | ENSGGOP00000013001 | Adenosine kinase. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.960 |
| ADK | AMPD3 | ENSGGOP00000005286 | ENSGGOP00000046645 | Adenosine kinase. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.954 |
| ADK | APRT | ENSGGOP00000005286 | ENSGGOP00000012324 | Adenosine kinase. | Adenine phosphoribosyltransferase. | 0.986 |
| ADK | HPRT1 | ENSGGOP00000005286 | ENSGGOP00000027942 | Adenosine kinase. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.461 |
| ADK | ITPA | ENSGGOP00000005286 | ENSGGOP00000008544 | Adenosine kinase. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.570 |
| ADSL | ADK | ENSGGOP00000014747 | ENSGGOP00000005286 | ADSL_C domain-containing protein. | Adenosine kinase. | 0.972 |
| ADSL | AK3 | ENSGGOP00000014747 | ENSGGOP00000023329 | ADSL_C domain-containing protein. | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 0.969 |
| ADSL | AMPD1 | ENSGGOP00000014747 | ENSGGOP00000036589 | ADSL_C domain-containing protein. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.936 |
| ADSL | AMPD2 | ENSGGOP00000014747 | ENSGGOP00000013001 | ADSL_C domain-containing protein. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.928 |
| ADSL | AMPD3 | ENSGGOP00000014747 | ENSGGOP00000046645 | ADSL_C domain-containing protein. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.935 |
| ADSL | APRT | ENSGGOP00000014747 | ENSGGOP00000012324 | ADSL_C domain-containing protein. | Adenine phosphoribosyltransferase. | 0.985 |
| ADSL | HPRT1 | ENSGGOP00000014747 | ENSGGOP00000027942 | ADSL_C domain-containing protein. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.726 |
| ADSL | IMPDH | ENSGGOP00000014747 | ENSGGOP00000012922 | ADSL_C domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.683 |
| ADSL | ITPA | ENSGGOP00000014747 | ENSGGOP00000008544 | ADSL_C domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.411 |
| AK3 | ADK | ENSGGOP00000023329 | ENSGGOP00000005286 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | Adenosine kinase. | 0.941 |
| AK3 | ADSL | ENSGGOP00000023329 | ENSGGOP00000014747 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | ADSL_C domain-containing protein. | 0.969 |
| AK3 | AMPD1 | ENSGGOP00000023329 | ENSGGOP00000036589 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.937 |
