STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F10Coagulation factor X. (488 aa)    
Predicted Functional Partners:
TFPI
Tissue factor pathway inhibitor.
    
 0.994
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
  
0.990
F7
Coagulation factor VII.
  
0.988
F3
Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
    
 0.982
F9
Coagulation factor IX.
  
 
0.975
F5
Coagulation factor V; Belongs to the multicopper oxidase family.
   
 0.975
G3S9Q7_GORGO
Uncharacterized protein; Belongs to the serpin family.
   
 0.951
ENSGGOP00000045598
SERPIN domain-containing protein; Belongs to the serpin family.
   
 0.951
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
   
 0.941
ASPH
Aspartate beta-hydroxylase.
    
 
 0.858
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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