STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CMBLCarboxymethylenebutenolidase homolog. (245 aa)    
Predicted Functional Partners:
ADHFE1
Fe-ADH domain-containing protein.
  
 
 0.899
PAICS
AIRC domain-containing protein.
   
  
 0.874
ZNF575
Uncharacterized protein.
      
 0.870
PRELID3B
PRELI domain containing 3B.
      
 0.870
BLOC1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]
      
 0.865
KCNIP3
Potassium voltage-gated channel interacting protein 3.
      
 0.860
SLC16A14
Solute carrier family 16 member 14.
   
  
 0.847
ENSGGOP00000034697
Hydroxyacyl-CoA dehydrogenase.
   
 
 0.817
CRYL1
Crystallin lambda 1.
   
 
 0.809
JOSD1
Josephin domain containing 1.
      
 0.807
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.