| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD22 | CD72 | ENSGGOP00000008903 | ENSGGOP00000020801 | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] | CD72 molecule. | 0.704 |
| CD22 | PTPN6 | ENSGGOP00000008903 | ENSGGOP00000013813 | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.994 |
| CD22 | SYK | ENSGGOP00000008903 | ENSGGOP00000010128 | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] | Tyrosine-protein kinase. | 0.843 |
| CD72 | CD22 | ENSGGOP00000020801 | ENSGGOP00000008903 | CD72 molecule. | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6- linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that b [...] | 0.704 |
| CD72 | PECAM1 | ENSGGOP00000020801 | ENSGGOP00000011255 | CD72 molecule. | Platelet and endothelial cell adhesion molecule 1. | 0.508 |
| CD72 | PTPN6 | ENSGGOP00000020801 | ENSGGOP00000013813 | CD72 molecule. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.981 |
| ENSGGOP00000030478 | G3QSH5_GORGO | ENSGGOP00000030478 | ENSGGOP00000005613 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.957 |
| ENSGGOP00000030478 | KDR | ENSGGOP00000030478 | ENSGGOP00000012526 | Tyrosine-protein kinase. | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.918 |
| ENSGGOP00000030478 | PIK3R1 | ENSGGOP00000030478 | ENSGGOP00000050489 | Tyrosine-protein kinase. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.988 |
| ENSGGOP00000030478 | PTPN6 | ENSGGOP00000030478 | ENSGGOP00000013813 | Tyrosine-protein kinase. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.994 |
| ENSGGOP00000030478 | SYK | ENSGGOP00000030478 | ENSGGOP00000010128 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.872 |
| G3QSH5_GORGO | ENSGGOP00000030478 | ENSGGOP00000005613 | ENSGGOP00000030478 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.957 |
| G3QSH5_GORGO | PIK3R1 | ENSGGOP00000005613 | ENSGGOP00000050489 | Tyrosine-protein kinase. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.959 |
| G3QSH5_GORGO | PTPN6 | ENSGGOP00000005613 | ENSGGOP00000013813 | Tyrosine-protein kinase. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.979 |
| G3QSH5_GORGO | SYK | ENSGGOP00000005613 | ENSGGOP00000010128 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.681 |
| KDR | ENSGGOP00000030478 | ENSGGOP00000012526 | ENSGGOP00000030478 | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Tyrosine-protein kinase. | 0.918 |
| KDR | PECAM1 | ENSGGOP00000012526 | ENSGGOP00000011255 | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Platelet and endothelial cell adhesion molecule 1. | 0.977 |
| KDR | PIK3R1 | ENSGGOP00000012526 | ENSGGOP00000050489 | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.989 |
| KDR | PTPN6 | ENSGGOP00000012526 | ENSGGOP00000013813 | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.981 |
| LCP2 | PECAM1 | ENSGGOP00000006455 | ENSGGOP00000011255 | Lymphocyte cytosolic protein 2. | Platelet and endothelial cell adhesion molecule 1. | 0.409 |
