STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALX4ALX homeobox 4. (409 aa)    
Predicted Functional Partners:
EXT2
Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.
      
 0.673
GLI3
GLI family zinc finger 3.
  
 
 0.636
RUNX2
Runt domain-containing protein.
     
 0.503
G3R860_GORGO
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.490
SIX3
Homeobox domain-containing protein.
    
 
 0.481
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 
 0.476
PAX9
Paired box 9.
      
 0.465
NEUROG1
Neurogenin 1.
   
  
 0.460
SATB2
DNA-binding protein SATB.
    
 
 0.459
MAFK
MAF bZIP transcription factor K.
    
 
 0.458
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.