| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BARD1 | BLM | ENSGGOP00000031076 | ENSGGOP00000007548 | BRCA1 associated RING domain 1. | BLM RecQ like helicase. | 0.759 |
| BARD1 | BRCA1 | ENSGGOP00000031076 | ENSGGOP00000023921 | BRCA1 associated RING domain 1. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.999 |
| BARD1 | BRCA2 | ENSGGOP00000031076 | ENSGGOP00000027226 | BRCA1 associated RING domain 1. | BRCA2 DNA repair associated. | 0.987 |
| BARD1 | CHEK1 | ENSGGOP00000031076 | ENSGGOP00000017130 | BRCA1 associated RING domain 1. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.795 |
| BARD1 | G3R2C0_GORGO | ENSGGOP00000031076 | ENSGGOP00000009366 | BRCA1 associated RING domain 1. | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. | 0.813 |
| BARD1 | G3RED9_GORGO | ENSGGOP00000031076 | ENSGGOP00000013922 | BRCA1 associated RING domain 1. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.983 |
| BARD1 | PALB2 | ENSGGOP00000031076 | ENSGGOP00000012506 | BRCA1 associated RING domain 1. | Partner and localizer of BRCA2. | 0.919 |
| BARD1 | RAD50 | ENSGGOP00000031076 | ENSGGOP00000001039 | BRCA1 associated RING domain 1. | Zinc-hook domain-containing protein. | 0.974 |
| BARD1 | RAD51AP1 | ENSGGOP00000031076 | ENSGGOP00000004360 | BRCA1 associated RING domain 1. | RAD51 associated protein 1. | 0.410 |
| BARD1 | RAD52 | ENSGGOP00000031076 | ENSGGOP00000006334 | BRCA1 associated RING domain 1. | RAD52 homolog, DNA repair protein. | 0.806 |
| BLM | BARD1 | ENSGGOP00000007548 | ENSGGOP00000031076 | BLM RecQ like helicase. | BRCA1 associated RING domain 1. | 0.759 |
| BLM | BRCA1 | ENSGGOP00000007548 | ENSGGOP00000023921 | BLM RecQ like helicase. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.940 |
| BLM | BRCA2 | ENSGGOP00000007548 | ENSGGOP00000027226 | BLM RecQ like helicase. | BRCA2 DNA repair associated. | 0.906 |
| BLM | CHEK1 | ENSGGOP00000007548 | ENSGGOP00000017130 | BLM RecQ like helicase. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.871 |
| BLM | G3R2C0_GORGO | ENSGGOP00000007548 | ENSGGOP00000009366 | BLM RecQ like helicase. | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. | 0.919 |
| BLM | G3RED9_GORGO | ENSGGOP00000007548 | ENSGGOP00000013922 | BLM RecQ like helicase. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.988 |
| BLM | PALB2 | ENSGGOP00000007548 | ENSGGOP00000012506 | BLM RecQ like helicase. | Partner and localizer of BRCA2. | 0.754 |
| BLM | RAD50 | ENSGGOP00000007548 | ENSGGOP00000001039 | BLM RecQ like helicase. | Zinc-hook domain-containing protein. | 0.948 |
| BLM | RAD51AP1 | ENSGGOP00000007548 | ENSGGOP00000004360 | BLM RecQ like helicase. | RAD51 associated protein 1. | 0.572 |
| BLM | RAD52 | ENSGGOP00000007548 | ENSGGOP00000006334 | BLM RecQ like helicase. | RAD52 homolog, DNA repair protein. | 0.882 |
