STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERBB4Receptor protein-tyrosine kinase. (1308 aa)    
Predicted Functional Partners:
ERBB2
Receptor protein-tyrosine kinase.
  
 
0.997
NRG1
Neuregulin 1.
    
 0.997
GRB2
Growth factor receptor bound protein 2.
    
 0.995
G3QZR8_GORGO
Uncharacterized protein.
    
 0.995
HBEGF
Heparin binding EGF like growth factor.
    
 0.994
NRG4
Neuregulin 4.
   
 0.994
SHC1
SHC adaptor protein 1.
    
 0.991
EREG
EGF-like domain-containing protein.
    
 0.990
EGF
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
   
 0.990
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
    
 0.990
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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