| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FSHB | FSHR | ENSGGOP00000017457 | ENSGGOP00000014079 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.998 |
| FSHB | GNB1 | ENSGGOP00000017457 | ENSGGOP00000035487 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | G protein subunit beta 1. | 0.611 |
| FSHB | GNB4 | ENSGGOP00000017457 | ENSGGOP00000025314 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | G protein subunit beta 4. | 0.429 |
| FSHB | GNG2 | ENSGGOP00000017457 | ENSGGOP00000029199 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | G protein gamma domain-containing protein. | 0.613 |
| FSHB | GNG4 | ENSGGOP00000017457 | ENSGGOP00000007723 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.428 |
| FSHB | TSHB | ENSGGOP00000017457 | ENSGGOP00000010131 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Thyroid stimulating hormone subunit beta. | 0.452 |
| FSHR | FSHB | ENSGGOP00000014079 | ENSGGOP00000017457 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | 0.998 |
| FSHR | G3QFE2_GORGO | ENSGGOP00000014079 | ENSGGOP00000001012 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | G protein subunit beta 5. | 0.922 |
| FSHR | GNAS | ENSGGOP00000014079 | ENSGGOP00000002801 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | GNAS complex locus. | 0.942 |
| FSHR | GNB1 | ENSGGOP00000014079 | ENSGGOP00000035487 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | G protein subunit beta 1. | 0.974 |
| FSHR | GNB2 | ENSGGOP00000014079 | ENSGGOP00000040379 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | G protein subunit beta 2. | 0.947 |
| FSHR | GNB3 | ENSGGOP00000014079 | ENSGGOP00000002568 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | G protein subunit beta 3. | 0.925 |
| FSHR | GNB4 | ENSGGOP00000014079 | ENSGGOP00000025314 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | G protein subunit beta 4. | 0.957 |
| FSHR | GNG2 | ENSGGOP00000014079 | ENSGGOP00000029199 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | G protein gamma domain-containing protein. | 0.959 |
| FSHR | GNG4 | ENSGGOP00000014079 | ENSGGOP00000007723 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.939 |
| FSHR | TSHB | ENSGGOP00000014079 | ENSGGOP00000010131 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Thyroid stimulating hormone subunit beta. | 0.979 |
| G3QFE2_GORGO | FSHR | ENSGGOP00000001012 | ENSGGOP00000014079 | G protein subunit beta 5. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.922 |
| G3QFE2_GORGO | GNAS | ENSGGOP00000001012 | ENSGGOP00000002801 | G protein subunit beta 5. | GNAS complex locus. | 0.967 |
| G3QFE2_GORGO | GNB1 | ENSGGOP00000001012 | ENSGGOP00000035487 | G protein subunit beta 5. | G protein subunit beta 1. | 0.962 |
| G3QFE2_GORGO | GNB2 | ENSGGOP00000001012 | ENSGGOP00000040379 | G protein subunit beta 5. | G protein subunit beta 2. | 0.948 |
