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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)    
Predicted Functional Partners:
FSHB
Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
   
 0.999
CGA
Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family.
    
 0.996
GNAS
GNAS complex locus.
    
 0.955
TSHB
Thyroid stimulating hormone subunit beta.
    
 0.930
POMC
Proopiomelanocortin.
   
 
 0.917
ADCYAP1
Adenylate cyclase activating polypeptide 1.
     
 0.914
NPPA
Natriuretic peptide A.
   
 
  0.908
VIP
Vasoactive intestinal peptide.
     
 0.908
GCG
Glucagon.
     
 0.908
ENSGGOP00000032065
Uncharacterized protein.
   
 
 0.904
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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