node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADCYAP1 | FSHR | ENSGGOP00000045801 | ENSGGOP00000014079 | Adenylate cyclase activating polypeptide 1. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.914 |
ADCYAP1 | GCG | ENSGGOP00000045801 | ENSGGOP00000026426 | Adenylate cyclase activating polypeptide 1. | Glucagon. | 0.594 |
ADCYAP1 | GNAS | ENSGGOP00000045801 | ENSGGOP00000002801 | Adenylate cyclase activating polypeptide 1. | GNAS complex locus. | 0.830 |
ADCYAP1 | POMC | ENSGGOP00000045801 | ENSGGOP00000003417 | Adenylate cyclase activating polypeptide 1. | Proopiomelanocortin. | 0.495 |
CGA | FSHB | ENSGGOP00000030475 | ENSGGOP00000017457 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | 0.999 |
CGA | FSHR | ENSGGOP00000030475 | ENSGGOP00000014079 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.996 |
CGA | GNAS | ENSGGOP00000030475 | ENSGGOP00000002801 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | GNAS complex locus. | 0.817 |
CGA | POMC | ENSGGOP00000030475 | ENSGGOP00000003417 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Proopiomelanocortin. | 0.750 |
CGA | TSHB | ENSGGOP00000030475 | ENSGGOP00000010131 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Thyroid stimulating hormone subunit beta. | 0.999 |
ENSGGOP00000032065 | FSHR | ENSGGOP00000032065 | ENSGGOP00000014079 | Uncharacterized protein. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.904 |
ENSGGOP00000032065 | GCG | ENSGGOP00000032065 | ENSGGOP00000026426 | Uncharacterized protein. | Glucagon. | 0.506 |
ENSGGOP00000032065 | GNAS | ENSGGOP00000032065 | ENSGGOP00000002801 | Uncharacterized protein. | GNAS complex locus. | 0.931 |
FSHB | CGA | ENSGGOP00000017457 | ENSGGOP00000030475 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | 0.999 |
FSHB | FSHR | ENSGGOP00000017457 | ENSGGOP00000014079 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.999 |
FSHB | POMC | ENSGGOP00000017457 | ENSGGOP00000003417 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Proopiomelanocortin. | 0.588 |
FSHB | TSHB | ENSGGOP00000017457 | ENSGGOP00000010131 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Thyroid stimulating hormone subunit beta. | 0.410 |
FSHR | ADCYAP1 | ENSGGOP00000014079 | ENSGGOP00000045801 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Adenylate cyclase activating polypeptide 1. | 0.914 |
FSHR | CGA | ENSGGOP00000014079 | ENSGGOP00000030475 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | 0.996 |
FSHR | ENSGGOP00000032065 | ENSGGOP00000014079 | ENSGGOP00000032065 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Uncharacterized protein. | 0.904 |
FSHR | FSHB | ENSGGOP00000014079 | ENSGGOP00000017457 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | 0.999 |