STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3RF26_GORGON-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (411 aa)    
Predicted Functional Partners:
SMPD1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
   
 0.968
SPHK1
Sphingosine kinase 1.
     
 0.961
G3RW37_GORGO
Neutral ceramidase.
     
 0.960
GALC
Galactosylceramidase.
     
 0.959
ACER1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.956
UGCG
UDP-glucose ceramide glucosyltransferase.
     
 0.951
CERS6
Ceramide synthase 6.
    
 0.951
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.946
GBA2
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
    
 0.946
CERS2
Ceramide synthase 2.
    
 0.946
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.