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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3RFH4_GORGOTyrosine-protein kinase. (508 aa)    
Predicted Functional Partners:
PAG1
Phosphoprotein membrane anchor with glycosphingolipid microdomains 1.
    
 0.883
SRC
Tyrosine-protein kinase.
  
0.794
YES1
Tyrosine-protein kinase.
  
0.793
LYN
Tyrosine-protein kinase.
  
0.757
HCK
Tyrosine-protein kinase.
  
0.751
ERBB2
Receptor protein-tyrosine kinase.
    
0.730
G3QMP2_GORGO
Protein tyrosine phosphatase non-receptor type 22.
   
 0.724
PTPN12
Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.
   
 0.724
CD48
CD48 molecule.
   
 0.708
SLAMF1
Signaling lymphocytic activation molecule family member 1.
   
 
 0.705
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.