STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D23TBC1 domain family member 23. (701 aa)    
Predicted Functional Partners:
OSGEP
Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
    
   0.732
GLRX3
Glutaredoxin 3.
    
   0.684
ENSGGOP00000050450
Uncharacterized protein.
    
   0.684
API5
Apoptosis inhibitor 5.
   
   0.571
C5H17orf75
Chromosome 17 open reading frame 75.
      
 0.568
TBC1D16
TBC1 domain family member 16.
      
 0.555
G3R0U7_GORGO
TBC1 domain family member 20.
      
 0.509
WASHC4
WASH complex subunit 4.
   
 
 0.508
FAM91A1
Family with sequence similarity 91 member A1.
   
  
 0.503
ENSGGOP00000030839
Uncharacterized protein.
   
  
 0.503
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.