| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADSL | AK3 | ENSGGOP00000014747 | ENSGGOP00000023329 | ADSL_C domain-containing protein. | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 0.969 |
| ADSL | G3R2Q9_GORGO | ENSGGOP00000014747 | ENSGGOP00000009520 | ADSL_C domain-containing protein. | 5'-nucleotidase domain containing 4. | 0.905 |
| ADSL | ITPA | ENSGGOP00000014747 | ENSGGOP00000008544 | ADSL_C domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.411 |
| ADSL | NT5C | ENSGGOP00000014747 | ENSGGOP00000004641 | ADSL_C domain-containing protein. | 5', 3'-nucleotidase, cytosolic. | 0.909 |
| ADSL | NT5C1B | ENSGGOP00000014747 | ENSGGOP00000043782 | ADSL_C domain-containing protein. | Uncharacterized protein. | 0.926 |
| ADSL | NT5C2 | ENSGGOP00000014747 | ENSGGOP00000012935 | ADSL_C domain-containing protein. | 5'-nucleotidase, cytosolic II. | 0.908 |
| ADSL | NT5E | ENSGGOP00000014747 | ENSGGOP00000000884 | ADSL_C domain-containing protein. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.931 |
| ADSL | NT5M | ENSGGOP00000014747 | ENSGGOP00000015749 | ADSL_C domain-containing protein. | 5',3'-nucleotidase, mitochondrial. | 0.906 |
| ADSL | PNP | ENSGGOP00000014747 | ENSGGOP00000027451 | ADSL_C domain-containing protein. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.466 |
| AK3 | ADSL | ENSGGOP00000023329 | ENSGGOP00000014747 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | ADSL_C domain-containing protein. | 0.969 |
| AK3 | G3R2Q9_GORGO | ENSGGOP00000023329 | ENSGGOP00000009520 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 5'-nucleotidase domain containing 4. | 0.900 |
| AK3 | NT5C | ENSGGOP00000023329 | ENSGGOP00000004641 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 5', 3'-nucleotidase, cytosolic. | 0.929 |
| AK3 | NT5C1B | ENSGGOP00000023329 | ENSGGOP00000043782 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | Uncharacterized protein. | 0.928 |
| AK3 | NT5C2 | ENSGGOP00000023329 | ENSGGOP00000012935 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 5'-nucleotidase, cytosolic II. | 0.900 |
| AK3 | NT5E | ENSGGOP00000023329 | ENSGGOP00000000884 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.904 |
| AK3 | NT5M | ENSGGOP00000023329 | ENSGGOP00000015749 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 5',3'-nucleotidase, mitochondrial. | 0.949 |
| AK3 | PNP | ENSGGOP00000023329 | ENSGGOP00000027451 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.401 |
| G3R2Q9_GORGO | ADSL | ENSGGOP00000009520 | ENSGGOP00000014747 | 5'-nucleotidase domain containing 4. | ADSL_C domain-containing protein. | 0.905 |
| G3R2Q9_GORGO | AK3 | ENSGGOP00000009520 | ENSGGOP00000023329 | 5'-nucleotidase domain containing 4. | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 0.900 |
| G3R2Q9_GORGO | ITPA | ENSGGOP00000009520 | ENSGGOP00000008544 | 5'-nucleotidase domain containing 4. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.908 |
