STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPC5Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (572 aa)    
Predicted Functional Partners:
CAD
Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.
   
  
 0.677
UNC5D
Unc-5 netrin receptor D.
    
 
 0.657
NOTUM
Notum, palmitoleoyl-protein carboxylesterase.
    
 0.656
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.633
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.618
GPC6
Glypican 6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
0.578
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
      
 0.546
DCN
Decorin; May affect the rate of fibrils formation.
    
 0.545
G3QW78_GORGO
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 
 0.543
SDC1
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 0.534
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.