STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSGGOP00000038159Hydroxysteroid 11-beta dehydrogenase 1 like. (334 aa)    
Predicted Functional Partners:
SEZ6L2
Seizure related 6 homolog like 2.
   
 0.587
ADORA2A
Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
    
 
 0.552
OXSM
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.506
G3RNV7_GORGO
2Fe-2S ferredoxin-type domain-containing protein.
   
 0.483
FDX1
2Fe-2S ferredoxin-type domain-containing protein.
   
 0.483
AASDH
Aminoadipate-semialdehyde dehydrogenase.
  
 0.457
SCP2
Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.456
FASN
Fatty acid synthase.
  
 0.452
G3QCT3_GORGO
Malonyl-CoA-acyl carrier protein transacylase.
  
 
 0.437
DHCR7
7-dehydrocholesterol reductase.
   
 
 0.424
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.