STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB22ARAB22A, member RAS oncogene family. (194 aa)    
Predicted Functional Partners:
RAB31
RAB31, member RAS oncogene family.
  
 
 
0.969
G3R475_GORGO
RAB guanine nucleotide exchange factor 1.
   
 0.955
G3RTS2_GORGO
A20-type domain-containing protein.
   
 0.934
ENSGGOP00000052295
A20-type domain-containing protein.
   
 0.928
RBSN
Rabenosyn, RAB effector.
   
 0.891
GDI1
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
   
 0.841
RABGGTA
Rab geranylgeranyltransferase subunit alpha.
    
 0.784
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 
 0.757
G3S7H0_GORGO
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 
 0.757
RABEP1
Rabaptin, RAB GTPase binding effector protein 1.
    
 0.719
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.