| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CASP3 | SNCA | ENSGGOP00000021659 | ENSGGOP00000027281 | Caspase 3; Belongs to the peptidase C14A family. | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] | 0.601 |
| CASP3 | SNCB | ENSGGOP00000021659 | ENSGGOP00000015452 | Caspase 3; Belongs to the peptidase C14A family. | Beta-synuclein; Belongs to the synuclein family. | 0.500 |
| CASP3 | UNC5A | ENSGGOP00000021659 | ENSGGOP00000042974 | Caspase 3; Belongs to the peptidase C14A family. | Unc-5 netrin receptor A. | 0.684 |
| CPLX1 | SNCB | ENSGGOP00000022313 | ENSGGOP00000015452 | Complexin 1. | Beta-synuclein; Belongs to the synuclein family. | 0.580 |
| NRSN2 | SLC30A9 | ENSGGOP00000006036 | ENSGGOP00000001834 | Neurensin 2. | Solute carrier family 30 member 9. | 0.467 |
| NRSN2 | SNCB | ENSGGOP00000006036 | ENSGGOP00000015452 | Neurensin 2. | Beta-synuclein; Belongs to the synuclein family. | 0.588 |
| PLP1 | SNCB | ENSGGOP00000016108 | ENSGGOP00000015452 | Proteolipid protein 1. | Beta-synuclein; Belongs to the synuclein family. | 0.468 |
| SLC30A9 | NRSN2 | ENSGGOP00000001834 | ENSGGOP00000006036 | Solute carrier family 30 member 9. | Neurensin 2. | 0.467 |
| SLC30A9 | SNCB | ENSGGOP00000001834 | ENSGGOP00000015452 | Solute carrier family 30 member 9. | Beta-synuclein; Belongs to the synuclein family. | 0.470 |
| SNCA | CASP3 | ENSGGOP00000027281 | ENSGGOP00000021659 | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] | Caspase 3; Belongs to the peptidase C14A family. | 0.601 |
| SNCA | SNCAIP | ENSGGOP00000027281 | ENSGGOP00000015067 | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] | Synuclein alpha interacting protein. | 0.978 |
| SNCA | SNCB | ENSGGOP00000027281 | ENSGGOP00000015452 | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] | Beta-synuclein; Belongs to the synuclein family. | 0.955 |
| SNCA | SNCG | ENSGGOP00000027281 | ENSGGOP00000051618 | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] | Gamma-synuclein; Belongs to the synuclein family. | 0.402 |
| SNCAIP | SNCA | ENSGGOP00000015067 | ENSGGOP00000027281 | Synuclein alpha interacting protein. | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] | 0.978 |
| SNCAIP | SNCB | ENSGGOP00000015067 | ENSGGOP00000015452 | Synuclein alpha interacting protein. | Beta-synuclein; Belongs to the synuclein family. | 0.756 |
| SNCAIP | SNCG | ENSGGOP00000015067 | ENSGGOP00000051618 | Synuclein alpha interacting protein. | Gamma-synuclein; Belongs to the synuclein family. | 0.756 |
| SNCB | CASP3 | ENSGGOP00000015452 | ENSGGOP00000021659 | Beta-synuclein; Belongs to the synuclein family. | Caspase 3; Belongs to the peptidase C14A family. | 0.500 |
| SNCB | CPLX1 | ENSGGOP00000015452 | ENSGGOP00000022313 | Beta-synuclein; Belongs to the synuclein family. | Complexin 1. | 0.580 |
| SNCB | NRSN2 | ENSGGOP00000015452 | ENSGGOP00000006036 | Beta-synuclein; Belongs to the synuclein family. | Neurensin 2. | 0.588 |
| SNCB | PLP1 | ENSGGOP00000015452 | ENSGGOP00000016108 | Beta-synuclein; Belongs to the synuclein family. | Proteolipid protein 1. | 0.468 |
