STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CALRCalreticulin. (417 aa)    
Predicted Functional Partners:
TAPBP
TAP binding protein.
    
 0.999
PDIA3
Protein disulfide-isomerase.
   
 0.998
CANX
Calnexin.
   
0.991
ENSGGOP00000034350
Uncharacterized protein.
   
 0.990
P4HB
Protein disulfide-isomerase.
   
 0.987
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.983
G3SHK6_GORGO
Uncharacterized protein.
   
 0.977
PDIA4
Protein disulfide-isomerase A4.
   
 0.970
G3RAL4_GORGO
Major histocompatibility complex, class I, E; Belongs to the MHC class I family.
    
 0.962
TAP1
Antigen peptide transporter 1; Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin (By similarity); Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
   
 0.957
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.