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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)    
Predicted Functional Partners:
MICAL1
Microtubule associated monooxygenase, calponin and LIM domain containing 1.
   
 
 0.942
ITSN2
Intersectin 2.
     
 0.909
BCAR3
BCAR3 adaptor protein, NSP family member.
    
 0.882
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.872
SMAD3
Mothers against decapentaplegic homolog.
    
 
 0.848
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.827
SRC
Tyrosine-protein kinase.
   
 0.827
CRKL
Uncharacterized protein.
    
 0.823
ENSGGOP00000048050
SH2 domain-containing protein.
    
 0.823
NIN
Ninein.
    
 
 0.806
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.