HDAC3 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSGGOP00000038823	ENSGGOP00000043083	ENSGGOP00000038823	ENSGGOP00000043083	Nuclear receptor corepressor 1.	Nuclear receptor corepressor 2.	0.977
ENSGGOP00000038823	G3QH29_GORGO	ENSGGOP00000038823	ENSGGOP00000001647	Nuclear receptor corepressor 1.	G protein pathway suppressor 2.	0.952
ENSGGOP00000038823	G3S905_GORGO	ENSGGOP00000038823	ENSGGOP00000024569	Nuclear receptor corepressor 1.	Uncharacterized protein.	0.952
ENSGGOP00000038823	HDAC1	ENSGGOP00000038823	ENSGGOP00000011454	Nuclear receptor corepressor 1.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.977
ENSGGOP00000038823	HDAC2	ENSGGOP00000038823	ENSGGOP00000005320	Nuclear receptor corepressor 1.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.947
ENSGGOP00000038823	HDAC3	ENSGGOP00000038823	ENSGGOP00000015976	Nuclear receptor corepressor 1.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.999
ENSGGOP00000038823	SIN3A	ENSGGOP00000038823	ENSGGOP00000035548	Nuclear receptor corepressor 1.	Uncharacterized protein.	0.991
ENSGGOP00000038823	TBL1X	ENSGGOP00000038823	ENSGGOP00000007381	Nuclear receptor corepressor 1.	Transducin beta like 1 X-linked.	0.940
ENSGGOP00000038823	TBL1XR1	ENSGGOP00000038823	ENSGGOP00000009311	Nuclear receptor corepressor 1.	Transducin beta like 1 X-linked receptor 1.	0.982
ENSGGOP00000038823	YY1	ENSGGOP00000038823	ENSGGOP00000024135	Nuclear receptor corepressor 1.	YY1 transcription factor.	0.613
ENSGGOP00000043083	ENSGGOP00000038823	ENSGGOP00000043083	ENSGGOP00000038823	Nuclear receptor corepressor 2.	Nuclear receptor corepressor 1.	0.977
ENSGGOP00000043083	G3QH29_GORGO	ENSGGOP00000043083	ENSGGOP00000001647	Nuclear receptor corepressor 2.	G protein pathway suppressor 2.	0.929
ENSGGOP00000043083	G3S905_GORGO	ENSGGOP00000043083	ENSGGOP00000024569	Nuclear receptor corepressor 2.	Uncharacterized protein.	0.929
ENSGGOP00000043083	HDAC1	ENSGGOP00000043083	ENSGGOP00000011454	Nuclear receptor corepressor 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.983
ENSGGOP00000043083	HDAC2	ENSGGOP00000043083	ENSGGOP00000005320	Nuclear receptor corepressor 2.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.972
ENSGGOP00000043083	HDAC3	ENSGGOP00000043083	ENSGGOP00000015976	Nuclear receptor corepressor 2.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.992
ENSGGOP00000043083	SIN3A	ENSGGOP00000043083	ENSGGOP00000035548	Nuclear receptor corepressor 2.	Uncharacterized protein.	0.986
ENSGGOP00000043083	TBL1X	ENSGGOP00000043083	ENSGGOP00000007381	Nuclear receptor corepressor 2.	Transducin beta like 1 X-linked.	0.950
ENSGGOP00000043083	TBL1XR1	ENSGGOP00000043083	ENSGGOP00000009311	Nuclear receptor corepressor 2.	Transducin beta like 1 X-linked receptor 1.	0.908
ENSGGOP00000043083	YY1	ENSGGOP00000043083	ENSGGOP00000024135	Nuclear receptor corepressor 2.	YY1 transcription factor.	0.427