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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DKKL1Dickkopf like acrosomal protein 1. (242 aa)    
Predicted Functional Partners:
CCDC155
Coiled-coil domain containing 155.
  
  
 0.739
TNK2
Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
  
 0.599
G3QCT9_GORGO
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.580
WNT2B
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
  
 0.576
DKK1
Dickkopf-related protein 1.
      
 0.571
CAGE1
Cancer antigen 1.
      
 0.571
DAGLA
Diacylglycerol lipase alpha.
      
 0.561
SIPA1L3
Signal induced proliferation associated 1 like 3.
      
 0.561
RAB11B
Uncharacterized protein.
     
 0.538
TNK1
Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
  
 0.534
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.