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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMCHD1Structural maintenance of chromosomes flexible hinge domain containing 1. (2005 aa)    
Predicted Functional Partners:
LRIF1
Ligand dependent nuclear receptor interacting factor 1.
    
 
 0.730
METTL4
Methyltransferase like 4; Belongs to the MT-A70-like family.
   
  
 0.728
G3QT16_GORGO
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
   
  
 0.675
PDS5A
PDS5 cohesin associated factor A.
   
  
 0.630
G3S285_GORGO
Uncharacterized protein.
      
 0.570
G3SIN0_GORGO
Uncharacterized protein.
      
 0.570
NT5C1B
Uncharacterized protein.
      
 0.566
AHCTF1
AT-hook containing transcription factor 1.
   
  
 0.553
PHIP
Pleckstrin homology domain interacting protein.
   
    0.548
SCAF11
SR-related CTD associated factor 11.
   
    0.544
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.