GRB7 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSGGOP00000034632	ERBB2	ENSGGOP00000034632	ENSGGOP00000004424	Recep_L_domain domain-containing protein.	Receptor protein-tyrosine kinase.	0.932
ENSGGOP00000034632	ERBB3	ENSGGOP00000034632	ENSGGOP00000037530	Recep_L_domain domain-containing protein.	Protein kinase domain-containing protein.	0.463
ENSGGOP00000034632	GRB7	ENSGGOP00000034632	ENSGGOP00000016933	Recep_L_domain domain-containing protein.	Growth factor receptor bound protein 7.	0.785
ENSGGOP00000034632	PTK2	ENSGGOP00000034632	ENSGGOP00000021868	Recep_L_domain domain-containing protein.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.490
ENSGGOP00000034632	RET	ENSGGOP00000034632	ENSGGOP00000003517	Recep_L_domain domain-containing protein.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.528
ERBB2	ENSGGOP00000034632	ENSGGOP00000004424	ENSGGOP00000034632	Receptor protein-tyrosine kinase.	Recep_L_domain domain-containing protein.	0.932
ERBB2	ERBB3	ENSGGOP00000004424	ENSGGOP00000037530	Receptor protein-tyrosine kinase.	Protein kinase domain-containing protein.	0.993
ERBB2	GRB7	ENSGGOP00000004424	ENSGGOP00000016933	Receptor protein-tyrosine kinase.	Growth factor receptor bound protein 7.	0.977
ERBB2	PTK2	ENSGGOP00000004424	ENSGGOP00000021868	Receptor protein-tyrosine kinase.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.985
ERBB2	RET	ENSGGOP00000004424	ENSGGOP00000003517	Receptor protein-tyrosine kinase.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.716
ERBB2	RND1	ENSGGOP00000004424	ENSGGOP00000006914	Receptor protein-tyrosine kinase.	Rho family GTPase 1.	0.671
ERBB3	ENSGGOP00000034632	ENSGGOP00000037530	ENSGGOP00000034632	Protein kinase domain-containing protein.	Recep_L_domain domain-containing protein.	0.463
ERBB3	ERBB2	ENSGGOP00000037530	ENSGGOP00000004424	Protein kinase domain-containing protein.	Receptor protein-tyrosine kinase.	0.993
ERBB3	GRB7	ENSGGOP00000037530	ENSGGOP00000016933	Protein kinase domain-containing protein.	Growth factor receptor bound protein 7.	0.785
ERBB3	PTK2	ENSGGOP00000037530	ENSGGOP00000021868	Protein kinase domain-containing protein.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.490
ERBB3	RET	ENSGGOP00000037530	ENSGGOP00000003517	Protein kinase domain-containing protein.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.528
FOXA2	GRB7	ENSGGOP00000020817	ENSGGOP00000016933	Forkhead box A2.	Growth factor receptor bound protein 7.	0.728
GRB7	ENSGGOP00000034632	ENSGGOP00000016933	ENSGGOP00000034632	Growth factor receptor bound protein 7.	Recep_L_domain domain-containing protein.	0.785
GRB7	ERBB2	ENSGGOP00000016933	ENSGGOP00000004424	Growth factor receptor bound protein 7.	Receptor protein-tyrosine kinase.	0.977
GRB7	ERBB3	ENSGGOP00000016933	ENSGGOP00000037530	Growth factor receptor bound protein 7.	Protein kinase domain-containing protein.	0.785