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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFR3AEFR3 homolog A. (848 aa)    
Predicted Functional Partners:
DOK6
Docking protein 6.
   
  
 0.880
DOK4
Docking protein 4.
   
  
 0.880
SEMA3E
Semaphorin 3E; Belongs to the semaphorin family.
      
 0.839
COL5A2
Collagen type V alpha 2 chain.
      
 0.798
TTC7A
Tetratricopeptide repeat domain 7A.
   
 
 0.757
TTC7B
Tetratricopeptide repeat domain 7B.
   
 
 0.639
G3RIN0_GORGO
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 
 0.535
PI4KA
Uncharacterized protein.
   
 
 0.535
ENSGGOP00000030162
PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.
   
 
 0.535
FAM126A
Family with sequence similarity 126 member A.
      
 0.437
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.