node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACAD9 | ECSIT | ENSGGOP00000009382 | ENSGGOP00000036409 | Acyl-CoA dehydrogenase family member 9. | ECSIT signalling integrator. | 0.999 |
ACAD9 | NDUFA12 | ENSGGOP00000009382 | ENSGGOP00000012562 | Acyl-CoA dehydrogenase family member 9. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.464 |
ACAD9 | NDUFA13 | ENSGGOP00000009382 | ENSGGOP00000005851 | Acyl-CoA dehydrogenase family member 9. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in [...] | 0.990 |
ACAD9 | NDUFAF1 | ENSGGOP00000009382 | ENSGGOP00000052230 | Acyl-CoA dehydrogenase family member 9. | Complex I intermediate-associated protein 30, mitochondrial; Chaperone protein involved in early stages of the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). | 0.999 |
ACAD9 | NDUFB11 | ENSGGOP00000009382 | ENSGGOP00000007685 | Acyl-CoA dehydrogenase family member 9. | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.477 |
ACAD9 | NDUFS1 | ENSGGOP00000009382 | ENSGGOP00000028060 | Acyl-CoA dehydrogenase family member 9. | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized (By sim [...] | 0.571 |
ACAD9 | NDUFS3 | ENSGGOP00000009382 | ENSGGOP00000014036 | Acyl-CoA dehydrogenase family member 9. | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | 0.993 |
ACAD9 | TIMMDC1 | ENSGGOP00000009382 | ENSGGOP00000024782 | Acyl-CoA dehydrogenase family member 9. | Uncharacterized protein. | 0.995 |
ACAD9 | TMEM126B | ENSGGOP00000009382 | ENSGGOP00000002102 | Acyl-CoA dehydrogenase family member 9. | Transmembrane protein 126B. | 0.999 |
ECSIT | ACAD9 | ENSGGOP00000036409 | ENSGGOP00000009382 | ECSIT signalling integrator. | Acyl-CoA dehydrogenase family member 9. | 0.999 |
ECSIT | G3SG37_GORGO | ENSGGOP00000036409 | ENSGGOP00000027073 | ECSIT signalling integrator. | AAA domain-containing protein. | 0.987 |
ECSIT | NDUFA12 | ENSGGOP00000036409 | ENSGGOP00000012562 | ECSIT signalling integrator. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.469 |
ECSIT | NDUFA13 | ENSGGOP00000036409 | ENSGGOP00000005851 | ECSIT signalling integrator. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in [...] | 0.994 |
ECSIT | NDUFAF1 | ENSGGOP00000036409 | ENSGGOP00000052230 | ECSIT signalling integrator. | Complex I intermediate-associated protein 30, mitochondrial; Chaperone protein involved in early stages of the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). | 0.999 |
ECSIT | NDUFB11 | ENSGGOP00000036409 | ENSGGOP00000007685 | ECSIT signalling integrator. | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.993 |
ECSIT | NDUFS1 | ENSGGOP00000036409 | ENSGGOP00000028060 | ECSIT signalling integrator. | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized (By sim [...] | 0.991 |
ECSIT | NDUFS3 | ENSGGOP00000036409 | ENSGGOP00000014036 | ECSIT signalling integrator. | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | 0.993 |
ECSIT | TIMMDC1 | ENSGGOP00000036409 | ENSGGOP00000024782 | ECSIT signalling integrator. | Uncharacterized protein. | 0.996 |
ECSIT | TMEM126B | ENSGGOP00000036409 | ENSGGOP00000002102 | ECSIT signalling integrator. | Transmembrane protein 126B. | 0.999 |
G3SG37_GORGO | ECSIT | ENSGGOP00000027073 | ENSGGOP00000036409 | AAA domain-containing protein. | ECSIT signalling integrator. | 0.987 |