STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SNX6Sorting nexin; Involved in several stages of intracellular trafficking. (418 aa)    
Predicted Functional Partners:
SNX2
PX domain-containing protein.
   
0.988
SNX1
Sorting nexin 1.
   
0.988
SNX5
Sorting nexin; Involved in several stages of intracellular trafficking.
  
 
0.979
SNX32
Sorting nexin; Involved in several stages of intracellular trafficking.
  
 
0.970
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 0.854
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.838
SNX4
Sorting nexin 4.
   
 0.833
ENSGGOP00000037430
Sorting nexin 3.
   
 0.810
VPS26A
Uncharacterized protein.
    
 0.800
SNX8
Sorting nexin 8.
   
 0.800
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.