| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMT | DHFR | ENSGGOP00000017517 | ENSGGOP00000042696 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.960 |
| AMT | DMGDH | ENSGGOP00000017517 | ENSGGOP00000003151 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Dimethylglycine dehydrogenase. | 0.906 |
| AMT | ENSGGOP00000035845 | ENSGGOP00000017517 | ENSGGOP00000035845 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Sarcosine dehydrogenase. | 0.906 |
| AMT | FPGS | ENSGGOP00000017517 | ENSGGOP00000000929 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.531 |
| AMT | G3R4K9_GORGO | ENSGGOP00000017517 | ENSGGOP00000010215 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.966 |
| AMT | MTHFD1 | ENSGGOP00000017517 | ENSGGOP00000018507 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. | 0.938 |
| AMT | MTHFD1L | ENSGGOP00000017517 | ENSGGOP00000003590 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. | 0.938 |
| AMT | SHMT1 | ENSGGOP00000017517 | ENSGGOP00000030416 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.971 |
| AMT | SHMT2 | ENSGGOP00000017517 | ENSGGOP00000009996 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.971 |
| AMT | TYMS | ENSGGOP00000017517 | ENSGGOP00000025166 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Thymidylate synthetase. | 0.959 |
| DHFR | AMT | ENSGGOP00000042696 | ENSGGOP00000017517 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.960 |
| DHFR | DMGDH | ENSGGOP00000042696 | ENSGGOP00000003151 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Dimethylglycine dehydrogenase. | 0.968 |
| DHFR | ENSGGOP00000035845 | ENSGGOP00000042696 | ENSGGOP00000035845 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Sarcosine dehydrogenase. | 0.979 |
| DHFR | FPGS | ENSGGOP00000042696 | ENSGGOP00000000929 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.988 |
| DHFR | G3R4K9_GORGO | ENSGGOP00000042696 | ENSGGOP00000010215 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.968 |
| DHFR | MTHFD1 | ENSGGOP00000042696 | ENSGGOP00000018507 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. | 0.963 |
| DHFR | MTHFD1L | ENSGGOP00000042696 | ENSGGOP00000003590 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. | 0.954 |
| DHFR | SHMT1 | ENSGGOP00000042696 | ENSGGOP00000030416 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.983 |
| DHFR | SHMT2 | ENSGGOP00000042696 | ENSGGOP00000009996 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.983 |
| DHFR | TYMS | ENSGGOP00000042696 | ENSGGOP00000025166 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | Thymidylate synthetase. | 0.999 |
