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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSGGOP00000045153Mindbomb E3 ubiquitin protein ligase 2. (979 aa)    
Predicted Functional Partners:
UBA52
Ubiquitin-like domain-containing protein.
    
 0.938
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
    
 0.909
TRAF2
TNF receptor-associated factor.
    
 0.893
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.888
CFLAR
CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family.
    
 0.867
G3QT76_GORGO
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
    
 0.846
TRADD
Death domain-containing protein.
    
  0.845
TRAF7
TNF receptor associated factor 7.
   
 0.843
PRKN
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.841
NFATC4
Nuclear factor of activated T cells 4.
    
 0.829
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.