STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3QJD0_GORGOSortilin related receptor 1. (2215 aa)    
Predicted Functional Partners:
APP
Amyloid beta precursor protein.
    
 0.996
GAK
Cyclin G associated kinase.
   
 0.919
APOE
Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]
    
 0.913
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 
 0.881
G3QLK2_GORGO
LDL receptor related protein associated protein 1.
    
 
 0.868
IGF2R
Insulin like growth factor 2 receptor.
    
 0.840
PICALM
Phosphatidylinositol binding clathrin assembly protein.
   
 
 0.840
GGA2
Golgi associated, gamma adaptin ear containing, ARF binding protein 2.
    
 
 0.832
NTS
Neurotensin.
    
 
 0.787
APLP2
Amyloid beta precursor like protein 2.
    
 0.746
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: medium (42%) [HD]