STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLCA4Chloride channel accessory 4. (894 aa)    
Predicted Functional Partners:
CLCA2
Chloride channel accessory 2.
  
  
 
0.919
CLCA1
Chloride channel accessory 1.
  
 
 
0.916
ANO2
Anoctamin.
     
 0.795
ANO1
Anoctamin.
     
 0.693
LIX1
Limb and CNS expressed 1.
   
    0.561
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]
   
 
 0.558
CWC25
CWC25 spliceosome associated protein homolog.
   
    0.514
MS4A12
Membrane spanning 4-domains A12.
   
  
 0.510
ZG16
Zymogen granule protein 16.
   
  
 0.509
G3QXK0_GORGO
Chromosome 1 open reading frame 109.
   
    0.505
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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