STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTRCChymotrypsin C; Belongs to the peptidase S1 family. (268 aa)    
Predicted Functional Partners:
CPA1
Carboxypeptidase A1.
   
 
 0.842
CEL
COesterase domain-containing protein.
   
 0.834
SPINK1
Serine peptidase inhibitor, Kazal type 1.
   
 0.740
CPA2
Carboxypeptidase A2.
   
 
 0.727
G3R0C5_GORGO
Chymotrypsin like elastase 3A; Belongs to the peptidase S1 family.
  
  
0.711
G3SBB8_GORGO
Chymotrypsin like elastase 3B; Belongs to the peptidase S1 family.
  
  
0.711
HEXD
Hexosaminidase D.
      
 0.672
PPY
Pancreatic polypeptide.
   
    0.665
ENSGGOP00000035613
Carboxypeptidase A4.
   
 
 0.627
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]
      
 0.578
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.