SOX10 protein (Gorilla gorilla) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

SOX10

HMG box domain-containing protein. (286 aa)

Predicted Functional Partners:

EGR2

0.967

PAX3

0.926

SMARCA4

0.925

HDAC2

0.908

PRX

0.805

ENSGGOP00000035916

0.797

MAG

0.760

PLP1

0.734

ENSGGOP00000036653

0.715

MITF

0.689

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGR2	ENSGGOP00000035916	ENSGGOP00000005181	ENSGGOP00000035916	Early growth response 2.	Uncharacterized protein.	0.786
EGR2	MAG	ENSGGOP00000005181	ENSGGOP00000048556	Early growth response 2.	Myelin associated glycoprotein.	0.789
EGR2	PRX	ENSGGOP00000005181	ENSGGOP00000010751	Early growth response 2.	Periaxin.	0.871
EGR2	SMARCA4	ENSGGOP00000005181	ENSGGOP00000034852	Early growth response 2.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4.	0.864
EGR2	SOX10	ENSGGOP00000005181	ENSGGOP00000019256	Early growth response 2.	HMG box domain-containing protein.	0.967
ENSGGOP00000035916	EGR2	ENSGGOP00000035916	ENSGGOP00000005181	Uncharacterized protein.	Early growth response 2.	0.786
ENSGGOP00000035916	MAG	ENSGGOP00000035916	ENSGGOP00000048556	Uncharacterized protein.	Myelin associated glycoprotein.	0.842
ENSGGOP00000035916	PLP1	ENSGGOP00000035916	ENSGGOP00000016108	Uncharacterized protein.	Proteolipid protein 1.	0.893
ENSGGOP00000035916	PRX	ENSGGOP00000035916	ENSGGOP00000010751	Uncharacterized protein.	Periaxin.	0.554
ENSGGOP00000035916	SOX10	ENSGGOP00000035916	ENSGGOP00000019256	Uncharacterized protein.	HMG box domain-containing protein.	0.797
ENSGGOP00000036653	MITF	ENSGGOP00000036653	ENSGGOP00000039766	Endothelin 3.	Melanocyte inducing transcription factor.	0.447
ENSGGOP00000036653	PAX3	ENSGGOP00000036653	ENSGGOP00000015260	Endothelin 3.	Paired box 3.	0.514
ENSGGOP00000036653	SOX10	ENSGGOP00000036653	ENSGGOP00000019256	Endothelin 3.	HMG box domain-containing protein.	0.715
HDAC2	SMARCA4	ENSGGOP00000005320	ENSGGOP00000034852	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4.	0.994
HDAC2	SOX10	ENSGGOP00000005320	ENSGGOP00000019256	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	HMG box domain-containing protein.	0.908
MAG	EGR2	ENSGGOP00000048556	ENSGGOP00000005181	Myelin associated glycoprotein.	Early growth response 2.	0.789
MAG	ENSGGOP00000035916	ENSGGOP00000048556	ENSGGOP00000035916	Myelin associated glycoprotein.	Uncharacterized protein.	0.842
MAG	PLP1	ENSGGOP00000048556	ENSGGOP00000016108	Myelin associated glycoprotein.	Proteolipid protein 1.	0.722
MAG	PRX	ENSGGOP00000048556	ENSGGOP00000010751	Myelin associated glycoprotein.	Periaxin.	0.497
MAG	SOX10	ENSGGOP00000048556	ENSGGOP00000019256	Myelin associated glycoprotein.	HMG box domain-containing protein.	0.760